A new drug that targets proteins responsible for helping cancer cells to repair damage to their DNA has shown promising anti-tumour activity in its first trial in humans. Some patients with a range of solid tumours, many of whom had been treated unsuccessfully for their cancer with other therapies, have seen their tumours shrink or […]
Tiny Trojan horses attack brain cancer cells
Scientists in Germany have developed a way of smuggling an anti-cancer drug past the protective blood-brain barrier and into brain tumours and metastases using a nanocarrier – a tiny capsule specially designed to pass through cell membranes and deliver its anti-cancer drug to the cancer cell. The blood-brain barrier is formed by a network of […]
Researchers map the way to personalised treatment for ovarian cancer
Researchers have shown that point mutations – mis-spellings in a single letter of genetic code – that drive the onset and growth of cancer cells can be detected successfully in advanced ovarian cancer using a technique called OncoMap. The finding opens the way for personalised medicine in which every patient could have their tumour screened, […]
Personalised medicine: tumour analysis reveals new opportunities for existing cancer drugs
Targeted cancer therapies such as trastuzumab (Herceptin), gefitinib (Iressa) and erlotinib (Tarceva) could be used to treat a wider range of cancers than previously thought, according to new research presented today (Wednesday) at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Berlin. Scientists in the USA have studied 20 genes that […]
Scientists identify potential new target for treating triple negative breast cancer
Scientists believe they may have found a new target for treating triple negative breast cancer – one of the more difficult breast cancers to treat successfully and for which there is no targeted therapy at present. Triple negative breast cancer (TNBC) is a cancer that does not express receptors for oestrogen (ER), progesterone (PR) or […]
Use of mild painkillers in pregnancy is associated with an increased risk of male reproductive problems
New evidence has emerged that the use of mild painkillers such as paracetamol, aspirin and ibuprofen, may be part of the reason for the increase in male reproductive disorders in recent decades. Research published in Europe’s leading reproductive medicine journal Human Reproduction today (Monday 8 November) shows that women who took a combination of more […]
Parental infertility and cerebral palsy in children born spontaneously or after IVF/ICSI
Doctors have known for some time that children born after fertility treatments such as in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) are at increased risk of cerebral palsy. However, it was not known whether this risk was due to the treatment itself, the higher frequency of preterm or multiple births, or a mechanism […]
Watching violent TV or video games desensitises teenagers and may promote more aggressive behaviour
Watching violent films, TV programmes or video games desensitises teenagers, blunts their emotional responses to aggression and potentially promotes aggressive attitudes and behaviour, according to new research published online today in the Oxford Journal Social Cognitive and Affective Neuroscience (Tuesday 19 October). Although previous research has suggested that people can become more aggressive and desensitised […]
MEPs and health professionals call for urgent action to tackle chronic diseases
Members of the European Parliament are calling on the Presidency of the EU and Member States to tackle urgently the problem of chronic non-communicable diseases that are responsible for 86% of all deaths in the WHO European Region. Their call is supported by an alliance of European health professionals, including ECCO – the European CanCer […]
Reaction to Bob Edwards winning the Nobel Prize for Medicine
In reaction to the news that Robert Edwards has been awarded the 2010 Nobel Prize for Medicine for his work pioneering in vitro fertilisation, Prof Martin Johnson, Professor of Reproductive Sciences at the University of Cambridge, said: “As one of Bob’s first research students, I’m naturally delighted that Bob Edwards has been awarded the Nobel […]