Milan, Italy: Results from the first study of the clinical application of next generation DNA sequencing (NGS) in screening embryos for genetic disease prior to implantation in patients undergoing in-vitro fertilisation treatments show that it is an effective reliable method of selecting the best embryos to transfer. The research was presented at the annual conference […]
Category: Genetics
Proposed amendments to EU Regulation on Medical Devices are counter to patients’ interests and unworkable, says ESHG
Recent amendments to the proposed Regulation on In Vitro Diagnostic Medical Devices (IVDs) currently before the European Parliament will restrict the rights of patients and doctors to carry out essential genetic testing, says the European Society of Human Genetics (ESHG) today (Monday 7 April 2014). Furthermore, an independent legal opinion now shows that the European […]
Genetic testing may improve selection of women with ER+ breast cancer for ten rather than five years of hormonal therapy
Glasgow, UK: Genetic analyses of results from 1125 postmenopausal women being treated for oestrogen responsive breast cancer have shown that some of them are more likely than others to have a late recurrence of their cancer and might benefit from ten years of hormone therapy rather than five. Prof Mitch Dowsett told the opening press […]
Anti-cancer drug T-DM1 benefits women with advanced breast cancer who have failed several previous treatments: results from TH3RESA trial
Amsterdam, The Netherlands: First results from a phase III clinical trial of the combination drug, T-DM1, show that it significantly improves the length of time before the disease worsens in women with advanced HER2 positive breast cancer whose cancer has recurred or progressed despite previous treatments, including trastuzumab and lapatinib. In a late-breaking presentation to […]
First randomised trial of targeted cancer medicine in all tumour types to be presented at ECC2013; results will pave the way for personalised treatment
A further step along the road to the personalisation of cancer medicine, where treatment is based on the individual molecular characteristics of tumours rather than their primary site, will be presented at the 2013 European Cancer Congress (ECC2013), which starts on Friday 27 September in Amsterdam, The Netherlands. Dr Christophe Le Tourneau, Head of the […]
Large study reveals increased cancer risks associated with family history of the disease
A family history of cancer increases the risk of other members of the family developing not only the same cancer (known as a concordant cancer) but also a different (discordant) cancer, according to a large study of 23,000 people in Italy and Switzerland. The research, published in the leading cancer journal Annals of Oncology [1], […]
Genetic research clarifies link between hypertension and Vitamin D deficiency
Paris, France: Low levels of vitamin D can trigger hypertension, according to the world’s largest study to examine the causal association between the two. Although observational studies have already shown this link, a large-scale genetic study was necessary before the cause and effect could be proven, researchers told the annual conference of the European Society […]
Diabetes drug shows promise in treatment of neurodegenerative disease
Paris, France: A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death. This is an important step along the road to the development of a therapy for the human disease for […]
Significant under-use of genetic testing for inherited cancers puts health of entire families at risk
Paris, France: A new study of the use of genetic testing for cancer-causing mutations in affected families in France has found that its take-up is very low. Professor Pascal Pujol, Head of the Cancer Genetics Department, Montpellier University Hospital, Montpellier, France, told the annual conference of the European Society of Human Genetics that analysis of […]
How ‘free will’ is implemented in the brain and is it possible to intervene in the process?
London, UK: Researchers have been able to identify the precise moment when a network of nerve cells (neurons) in the brain creates the signal to perform an action, before a person is even aware of deciding to take that action. Now they are building on this work to make initial attempts to interfere with consciously […]