Final analysis of the ALEXANDRA/IMpassion030 phase 3 trial Milan, Italy: Patients with triple-negative breast cancer do not benefit from the addition of atezolizumab to their post-surgery chemotherapy treatment, according to the results of a large phase 3 clinical trial presented at the 14th European Breast Cancer Conference. Triple negative breast cancer, so-called because the cancer […]
Category: Cancer
Exercise helps patients with advanced breast cancer, especially if they are suffering with pain
Milan, Italy: Taking part in an exercise programme reduced pain and fatigue, and improved quality of life for people with metastatic breast cancer, according to new results of a trial presented at the 14th European Breast Cancer Conference. Although patients of all ages benefitted from exercise, researchers saw the greatest improvement among patients aged under […]
Genetic test identifies patients with triple negative breast cancer who are unlikely to respond to immunotherapies
New results from the I-SPY2 phase 2 clinical trial Milan, Italy: Researchers have developed a genetic test that can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy drugs. This means that patients who are unlikely to respond to these drugs can avoid the adverse side effects associated with them and […]
Families of men with fertility problems show distinct patterns of increased risk for several types of cancer
For the first time researchers have identified patterns of risk for several different types of cancer in men with fertility problems and their families. The study, which is published in Human Reproduction [1], one of the world’s leading reproductive medicine journals, found that families of men who have very few or no sperm in their […]
Obesity and alcohol are contributing to increases in bowel cancer rates among young adults
Experts predict death rates from all cancers for the EU and UK for 2024 Overweight and obesity are contributing to rising death rates from bowel cancer among people aged 25-49 years in the European Union (EU) and the UK, although death rates from this type of cancer are decreasing overall across Europe. These findings are […]
Aid agencies are failing patients with breast cancer in war zones meaning more will develop advanced disease
Lisbon, Portugal: Patients with breast cancer in conflict zones around the world are being “massively under-served” by governments, UN aid agencies and other non-governmental organisations (NGOs), Professor Richard Sullivan told the Advanced Breast Cancer Seventh International Consensus Conference (ABC 7) in a video presentation from the Rafah crossing where he is working with the United […]
People with advanced breast cancer are forced out of work with a cost to themselves and the economy
Lisbon, Portugal: The majority of people living with advanced breast cancer give up working against their will, according to research presented at the Advanced Breast Cancer Seventh International Consensus Conference (ABC 7). [1] As well as the personal costs of being out of work, the new study shows that there is a significant overall cost […]
Latest results from PHOEBE trial show patients with advanced HER2-positive breast cancer live longer on pyrotinib
Lisbon, Portugal: Patients with HER2-positive breast cancer that has started to spread to other parts of the body survive for longer if they are treated with a new drug called pyrotinib, according to results from the longest follow-up of the PHOEBE randomised clinical trial in China. Presenting the latest results at the Advanced Breast Cancer […]
Research brings hope for early treatment of brain degeneration in ‘children of the night’
Glasgow, UK: Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterised by an inability to repair skin damage caused by ultraviolet (UV) light. As a result, patients with XP develop skin cancers, usually in childhood. Once diagnosed, they can be protected by avoiding sunlight (hence sometimes being called ‘children of the night’), wearing […]
Polygenic risk scores could improve colorectal cancer screening
Glasgow, UK: Rates of colorectal cancer are high despite widespread adoption of screening programmes in many high-income European countries. Such programmes tend to use a one-size-fits-all approach where most people are screened starting from the same age, and no individual factors are considered in organised population screening. Now, based on one of the largest genomics […]